Voluntary wheel running reduces voluntary consumption of ethanol in mice: identification of candidate genes through striatal gene expression profiling
نویسندگان
چکیده
منابع مشابه
MEMRI Study of Mice Cerebellar Activation after Voluntary Wheel Running
INTRODUCTION: There is increasing interest in studying functional and cellular effects of environmental stimuli for better intervention in neurological rehabilitation [1, 2]. Recent studies have been using BOLD-fMRI to detect the neural activity in living animals [3] and human [4]. However it is technically difficult to apply BOLD-fMRI to nonrestrained animals due to its extreme susceptibility ...
متن کاملNeurobiology of Mice Selected for High Voluntary Wheel-running Activity.
Selective breeding of house mice has been used to study the evolution of locomotor behavior. Our model consists of 4 replicate lines selectively bred for high voluntary wheel running (High-Runner) and 4 bred randomly (Control). The major changes in High-Runner lines appear to have taken place in the brain rather than in capacities for exercise. Their neurobiological profile resembles features o...
متن کاملNeurobiology of Mice Selected for High Voluntary Wheel-running Activity1
SYNOPSIS. Selective breeding of house mice has been used to study the evolution of locomotor behavior. Our model consists of 4 replicate lines selectively bred for high voluntary wheel running (High-Runner) and 4 bred randomly (Control). The major changes in High-Runner lines appear to have taken place in the brain rather than in capacities for exercise. Their neurobiological profile resembles ...
متن کاملHigh Fat High Sugar Diet Reduces Voluntary Wheel Running in Mice Independent of Sex Hormone Involvement
Introduction: Indirect results in humans suggest that chronic overfeeding decreases physical activity with few suggestions regarding what mechanism(s) may link overfeeding and decreased activity. The primary sex hormones are known regulators of activity and there are reports that chronic overfeeding alters sex hormone levels. Thepurpose of this study was to determine if chronic overfeeding alte...
متن کاملVoluntary wheel running attenuates lipopolysaccharide-induced liver inflammation in mice.
Sepsis induces an acute inflammatory response in the liver, which can lead to organ failure and death. Given the anti-inflammatory effects of exercise, we hypothesized that habitual physical activity could protect against acute sepsis-induced liver inflammation via mechanisms, including heat shock protein (HSP) 70/72. Male C57BL/6J mice (n = 80, ∼8 wk of age) engaged in physical activity via vo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genes, Brain and Behavior
سال: 2016
ISSN: 1601-1848
DOI: 10.1111/gbb.12294